Corentin BEDART, PhD, PharmD

Corentin BEDART, PhD, PharmD

Associate Professor

Chemoinformatics Bioinformatics Software developer Machine learning Pharmacist
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Projects

GPR35

Principal Investigator

Elucidation of the atomic-level pharmacology of GPR35 and identification of new, highly selective agonists, ideally possessing a biased signaling profile toward different biological response cascades.

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ANDROMEDA

Principal Investigator

ANDROMEDA : a drug discovery library software that unifies laboratory data with computational drug discovery

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Transcriptomic analysis of bulk and single cell RNA sequencing

Principal Investigator

Support for the analysis of INFINITE transcriptomic data obtained by bulk and single-cell RNA-Seq.

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Digestive mucins

Team Member

Study of digestive mucins Muc5b and Muc5ac, in collaboration with Dr. Jean-Luc DESSEYN, INFINITE

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FFAR4 (GPR120)

Team Member

Leveraged homology modeling and molecular dynamics to map the structural activation of FFAR4 (GPR120), identifying novel pharmacophore constraints for the next generation of anti-obesity therapeutics.

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P2X7

Team Member

Elucidation of the mechanism of action of the homotrimeric channel receptor P2X7 and identification of novel positive and negative allosteric modulators

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SINAPs v2

Principal Investigator

Development of version 2 of SINAPs, a tool designed to automate the identification and 3D visualization of key molecular interaction networks that drive protein activation and bioactive states

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